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Herein, we report a substrate-directed diverse synthetic strategy toward two kinds of structurally intriguing fused indole polycycles through Rh(II)-catalyzed cascade reactions of bis(diazo)indolin-2-ones with enaminones. The subtle structural changes in… Click to show full abstract
Herein, we report a substrate-directed diverse synthetic strategy toward two kinds of structurally intriguing fused indole polycycles through Rh(II)-catalyzed cascade reactions of bis(diazo)indolin-2-ones with enaminones. The subtle structural changes in enaminones lead to different reactivities. Cyclic enaminones produce indolo[2,3-b]indoles, whereas acyclic ones afford oxazolo[3,2-a]indoles.
Keywords:
substrate directed;
catalyzed cascade;
fused indole;
cascade reactions;
indole polycycles;
polycycles catalyzed
Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!