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Gold nanoparticles bearing a clinically used non-antibiotic drug for combating multi-drug resistant bacteria.

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We introduce N-acetyl-L-cysteine (NAC), a clinically used non-antibiotic drug, to the synthesis of antibacterial gold nanoparticles (Au_NAC). Au_NAC shows excellent antibacterial activities against multi-drug resistant (MDR) Gram-negative bacteria and possesses… Click to show full abstract

We introduce N-acetyl-L-cysteine (NAC), a clinically used non-antibiotic drug, to the synthesis of antibacterial gold nanoparticles (Au_NAC). Au_NAC shows excellent antibacterial activities against multi-drug resistant (MDR) Gram-negative bacteria and possesses wound healing capabilities. We provide a new direction for antibiotic design and novel uses of known drugs.

Keywords: gold nanoparticles; non antibiotic; used non; antibiotic drug; clinically used; drug

Journal Title: Chemical communications
Year Published: 2022

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