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A reactive stimuli responsive fluorescent polyaminoamide nanogel (NANO-PAMAM) is synthesized via an aza-Michael polyaddition reaction in water. In the next stage, doxorubicin (a FRET acceptor) is covalently linked with the… Click to show full abstract
A reactive stimuli responsive fluorescent polyaminoamide nanogel (NANO-PAMAM) is synthesized via an aza-Michael polyaddition reaction in water. In the next stage, doxorubicin (a FRET acceptor) is covalently linked with the nanogel (NANO-PAMAM, a nonconventional FRET donor) to form a ratiometric nanosensor for temperature and pH sensing. MTT assay revealed comparable biocompatibility of the donor nanogels (NANO-PAMAM) and nanosensors (NANO-PAMAM-DOX).
Keywords:
stimuli responsive;
nano pamam;
donor;
responsive fluorescent;
temperature sensing
Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!