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Quantum yield enhancement of firefly bioluminescence with biomolecular condensates.

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The enzymatic luminescence reactions of fireflies are accelerated in the presence of biomolecular condensates comprising a positively charged peptide and ATP. We revealed that this acceleration is caused by the… Click to show full abstract

The enzymatic luminescence reactions of fireflies are accelerated in the presence of biomolecular condensates comprising a positively charged peptide and ATP. We revealed that this acceleration is caused by the enrichment of reaction elements, local pH changes, and promotion of inhibitory intermediate dissociation, improving the bioluminescence quantum yield by approximately 10%.

Keywords: bioluminescence; quantum yield; yield enhancement; enhancement firefly; biomolecular condensates

Journal Title: Chemical communications
Year Published: 2022

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