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The water-mediated tosylation of alkenes with tosyl cyanide was discovered. Experimental investigations revealed that the reaction was initiated by the in situ formation of sulfinyl sulfone in the presence of… Click to show full abstract
The water-mediated tosylation of alkenes with tosyl cyanide was discovered. Experimental investigations revealed that the reaction was initiated by the in situ formation of sulfinyl sulfone in the presence of water. The sulfinyl sulfone species decomposed to a sulfonyl radical and a sulfinyl radical through homolytic fission. The vinyl sulfone was afforded via sequential addition of the alkene to the sulfonyl radical and the sulfinyl radical, followed by β-elimination of a sulfinyl moiety.
Keywords:
water;
tosyl cyanide;
tosylation alkenes;
water mediated;
alkenes tosyl
Journal Title: Chemical communications
Year Published: 2023
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Journal Title: Chemical communications
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!