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A new dual-cationic amphiphilic AIEgen TPhBT-PyP with NIR emission and efficient 1O2 generation was designed. The amphiphilicity of TPhBT-PyP was tuned with dual-positive charges of pyridinium and TPP groups, efficiently… Click to show full abstract
A new dual-cationic amphiphilic AIEgen TPhBT-PyP with NIR emission and efficient 1O2 generation was designed. The amphiphilicity of TPhBT-PyP was tuned with dual-positive charges of pyridinium and TPP groups, efficiently targeting mitochondria and distinguishing Gram-positive bacteria. TPhBT-PyP performed well in photodynamic therapy, inducing cancer cell apoptosis and killing S. aureus bacteria.
Keywords:
cationic amphiphilic;
tphbt pyp;
mitochondria targeting;
photodynamic therapy;
targeting nir
Journal Title: Chemical communications
Year Published: 2023
Link to full text (if available)
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Journal Title: Chemical communications
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!