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Anticancer SAR Establishment and α/β-Tubulin Isoforms Specific Targeting: A Detailed Insight of Anticancer potential of 4H-Chromene derivatives

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4H-Chromene derivatives are promising anticancer compounds known to bind within the colchicine binding site of tubulin protein. Among these 2-amino-4-phenyl-4H-benzo[h]chromene-3-carbonitrile based 4H-Chromenes scaffold is known to produce a significant impact... Click to show full abstract

4H-Chromene derivatives are promising anticancer compounds known to bind within the colchicine binding site of tubulin protein. Among these 2-amino-4-phenyl-4H-benzo[h]chromene-3-carbonitrile based 4H-Chromenes scaffold is known to produce a significant impact...

Keywords: chromene derivatives; establishment tubulin; chromene; anticancer sar; sar establishment

Journal Title: New Journal of Chemistry
Year Published: 2023

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