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The asymmetric total synthesis of four lignans, dimethylmatairesinol, matairesinol, (−)-niranthin, and (+)-niranthin has been achieved using reductive ring-opening of cyclopropanes. Moreover, we performed bioassays of the synthesized (+)- and (−)-niranthins… Click to show full abstract
The asymmetric total synthesis of four lignans, dimethylmatairesinol, matairesinol, (−)-niranthin, and (+)-niranthin has been achieved using reductive ring-opening of cyclopropanes. Moreover, we performed bioassays of the synthesized (+)- and (−)-niranthins using hepatitis B and influenza viruses, which revealed the relationship between the enantiomeric structure and the anti-viral activity of niranthin.
Keywords:
influenza viruses;
hepatitis influenza;
asymmetric total;
synthesis four;
total synthesis
Journal Title: RSC Advances
Year Published: 2022
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2022
Link to full text (if available)
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recommendations!