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Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method

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An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C–H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage… Click to show full abstract

An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C–H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%.

Keywords: bond cleavage; electrochemical method; iii catalysed

Journal Title: RSC Advances
Year Published: 2022

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