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A copper-catalyzed three-component carboboration of acetylene with B2Pin2 and Michael acceptors is reported. In this reaction, a cheap and abundant C2 chemical feedstock, acetylene, was used as a starting material… Click to show full abstract
A copper-catalyzed three-component carboboration of acetylene with B2Pin2 and Michael acceptors is reported. In this reaction, a cheap and abundant C2 chemical feedstock, acetylene, was used as a starting material to afford cis-alkenyl boronates bearing a homoallylic carbonyl group. The reaction was robust and could be reliably performed on the molar scale. Furthermore, the resulting cis-alkenyl boronates could be converted to diverse functionalized molecules with ease.
Keywords:
acetylene;
michael acceptors;
carboboration acetylene;
catalyzed carboboration
Journal Title: Chemical Science
Year Published: 2022
Link to full text (if available)
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Journal Title: Chemical Science
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!