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Morpholine-modified permethyl β-cyclodextrin supramolecular nanoparticles for precise dual-targeted imaging.

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Possessing dual-targeted agents toward the lysosome and cancer cells, a ternary supramolecular assembly was constructed by a morpholine-modified permethyl β-cyclodextrin, sulfonated porphyrin, and folic acid-modified chitosan via multivalent interactions. As… Click to show full abstract

Possessing dual-targeted agents toward the lysosome and cancer cells, a ternary supramolecular assembly was constructed by a morpholine-modified permethyl β-cyclodextrin, sulfonated porphyrin, and folic acid-modified chitosan via multivalent interactions. As compared with free porphyrin, the obtained ternary supramolecular assembly showed promoted photodynamic effect and achieved dual-targeted precise imaging in cancer cells.

Keywords: dual targeted; permethyl cyclodextrin; morpholine modified; cyclodextrin supramolecular; modified permethyl

Journal Title: Chemical communications
Year Published: 2023

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