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In situ evaluation of in vivo sialylation with a dual-color imaging strategy

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This work designs a functional dendrimer probe to conveniently identify newly generated sialic acid groups in vivo with a dual-color imaging strategy, which achieves in situ semiquantitative evaluation of the… Click to show full abstract

This work designs a functional dendrimer probe to conveniently identify newly generated sialic acid groups in vivo with a dual-color imaging strategy, which achieves in situ semiquantitative evaluation of the sialylation difference between tumor and normal tissues to reveal sialylation-related biological events and promote clinical tumor diagnosis.

Keywords: sialylation; imaging strategy; dual color; color imaging

Journal Title: Chemical Communications
Year Published: 2023

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