Bismuth(III) triflate-catalyzed [4+2]-annulation of cyclic N-sulfonyl ketimines (derived from saccharin) and alkynyl alcohols (4-pentyn-1-ols and 5-hexyn-1-ols) has been reported. This cascade annulation provides a diverse array of polycyclic spiro-and-fused N,O-ketals… Click to show full abstract
Bismuth(III) triflate-catalyzed [4+2]-annulation of cyclic N-sulfonyl ketimines (derived from saccharin) and alkynyl alcohols (4-pentyn-1-ols and 5-hexyn-1-ols) has been reported. This cascade annulation provides a diverse array of polycyclic spiro-and-fused N,O-ketals with excellent substrate scope, good isolated yields, and diastereoselectivities under mild reaction conditions.
Keywords:
annulation;
polycyclic spiro;
cyclic sulfonyl;
annulation cyclic;
sulfonyl ketimines;
catalyzed annulation
Journal Title: Chemical communications
Year Published: 2024
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Journal Title: Chemical communications
Year Published: 2024
Link to full text (if available)
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recommendations!