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Enhancing Dissolution and Bacteriostatic Activity of Trimethoprim through Salt Formation

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Trimethoprim (TMP) is a commonly used BCS class II antibiotic, the water solubility of which needs to be improved to overcome the limitations in oral administration. Herein, We combined TMP... Click to show full abstract

Trimethoprim (TMP) is a commonly used BCS class II antibiotic, the water solubility of which needs to be improved to overcome the limitations in oral administration. Herein, We combined TMP...

Keywords: trimethoprim salt; bacteriostatic activity; salt formation; enhancing dissolution; activity trimethoprim; dissolution bacteriostatic

Journal Title: CrystEngComm
Year Published: 2023

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