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LC-MS identification and cytotoxic assessment of jaspamide and its congeners from the sponge jaspis diastra

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Jaspamide (jasplakinolide; NSC-613009) is a cytotoxic cyclic polypeptide that was initially isolated from the sponge Jaspis cf. Johnston. It displayed anti-tumor, anti-fungal and insecticidal activities, among others. Herein, an LC-MS/MS... Click to show full abstract

Jaspamide (jasplakinolide; NSC-613009) is a cytotoxic cyclic polypeptide that was initially isolated from the sponge Jaspis cf. Johnston. It displayed anti-tumor, anti-fungal and insecticidal activities, among others. Herein, an LC-MS/MS...

Keywords: jaspamide; sponge jaspis; identification cytotoxic; assessment jaspamide; cytotoxic assessment; jaspamide congeners

Journal Title: New Journal of Chemistry
Year Published: 2023

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