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Binding symmetric porphyrins to c-MYC promoter Pu24I G-quadruplex: toward more specific ligand recognition by flanking bases

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Stabilization of G-quadruplexes formed in the promotor regions of oncogenes with small molecules is recognized as a convenient method to control oncogenes' overexpression in cancer cells. Due to a huge... Click to show full abstract

Stabilization of G-quadruplexes formed in the promotor regions of oncogenes with small molecules is recognized as a convenient method to control oncogenes' overexpression in cancer cells. Due to a huge...

Keywords: symmetric porphyrins; promoter pu24i; pu24i quadruplex; porphyrins myc; myc promoter; binding symmetric

Journal Title: New Journal of Chemistry
Year Published: 2023

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