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Dissecting the biosynthesis of the polyketide alkaloid lydicamycin using a complex metabolic network

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Microorganisms produce a great number of therapeutically interesting and structurally diverse natural products through modular biosynthetic assembly lines, i.e., type I polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). Lydicamycins... Click to show full abstract

Microorganisms produce a great number of therapeutically interesting and structurally diverse natural products through modular biosynthetic assembly lines, i.e., type I polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). Lydicamycins...

Keywords: biosynthesis polyketide; dissecting biosynthesis; lydicamycin using; polyketide; polyketide alkaloid; alkaloid lydicamycin

Journal Title: New Journal of Chemistry
Year Published: 2023

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