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Synthesis and inhibitory activity against MurA and MurZ enzymes of 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds having piperidine and morpholine rings

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A series of D-glucose-conjugated 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds 12a-g & 13a-g having piperidine and morpholine rings were synthesized by click chemistry between corresponding propargyl derivatives and azide of D-glucose using CuI@Montmorillonite... Click to show full abstract

A series of D-glucose-conjugated 4H-pyrano[2,3-d]pyrimidine−1H-1,2,3-triazole hybrid compounds 12a-g & 13a-g having piperidine and morpholine rings were synthesized by click chemistry between corresponding propargyl derivatives and azide of D-glucose using CuI@Montmorillonite...

Keywords: piperidine morpholine; chemistry; pyrimidine triazole; hybrid compounds; pyrano pyrimidine; triazole hybrid

Journal Title: New Journal of Chemistry
Year Published: 2023

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