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Efficient Synthesis of Quinolines through Alkali Catalysed Cascade Oppenauer Oxidation/Condensation of Amino Alcohols with Ketones

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We report an alkali catalysed dehydrogenative coupling between amino alcohols and ketones. This reaction is using NaH (5-20 mol%) as the sole catalyst, achieving the hydride transferred from the alpha-carbon... Click to show full abstract

We report an alkali catalysed dehydrogenative coupling between amino alcohols and ketones. This reaction is using NaH (5-20 mol%) as the sole catalyst, achieving the hydride transferred from the alpha-carbon...

Keywords: alkali catalysed; synthesis quinolines; alcohols ketones; efficient synthesis; amino alcohols

Journal Title: New Journal of Chemistry
Year Published: 2023

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