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Tuning the enzyme-like activity of peptide-nanoparticle conjugates with amino acid sequences.

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We constructed peptide-nanoparticle conjugates (AuNP@CDs-Azo-peptide) by self-assembly of cyclodextrin capped gold nanoparticles (AuNP@CDs) and azobenzene terminated peptide (Azo-peptide) through host-guest interactions. AuNP@CDs-Azo-peptide shows hydrolase-like activity, which is tuned by amino… Click to show full abstract

We constructed peptide-nanoparticle conjugates (AuNP@CDs-Azo-peptide) by self-assembly of cyclodextrin capped gold nanoparticles (AuNP@CDs) and azobenzene terminated peptide (Azo-peptide) through host-guest interactions. AuNP@CDs-Azo-peptide shows hydrolase-like activity, which is tuned by amino acid sequences.

Keywords: acid sequences; like activity; nanoparticle conjugates; amino acid; peptide nanoparticle

Journal Title: Nanoscale
Year Published: 2023

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