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DIC-Borane-Catalyzed Selective Methylation of Primary Amines with CO2 Using Boranes as Reducing Agents

The selective reductive N-methylation and N,N-dimethylation of primary amines using CO2 are some of the most significant challenges faced by organic chemists. Herein, we report the highly selective N,N’-diisopropylcarbodiimide-catalyzed methylation... Click to show full abstract

The selective reductive N-methylation and N,N-dimethylation of primary amines using CO2 are some of the most significant challenges faced by organic chemists. Herein, we report the highly selective N,N’-diisopropylcarbodiimide-catalyzed methylation...

Keywords: methylation; selective methylation; borane catalyzed; dic borane; primary amines; catalyzed selective

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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