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Stereoselective access to 2-deoxy-2-trifluoromethyl sugar mimetics by trifluoromethyl-directed 1,2-trans glycosylation

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A general methodology featuring a trifluoromethyl-directed 1,2-trans glycosylation reaction as a key step has been developed to give access to various 2-CF3-glycoconjugates, including carbohydrate epitopes, amino acids, and lipids. Click to show full abstract

A general methodology featuring a trifluoromethyl-directed 1,2-trans glycosylation reaction as a key step has been developed to give access to various 2-CF3-glycoconjugates, including carbohydrate epitopes, amino acids, and lipids.

Keywords: directed trans; trifluoromethyl directed; trans glycosylation; stereoselective access

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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