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Enantioselective Construction of Dihydropyranone-Fused Indoles by [3+3] Annulation of in Situ-Derived Indolin-3-ones and Unsaturated Carboxylic Ester

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We develop a N-heterocyclic carbene (NHC) and base-mediated [3+3] annulation reaction of the unsaturated carboxylic ester and sulfonium salts for the rapid and direct access to the enantioselective dihydropyrano[3,2-b]indoles. Easily... Click to show full abstract

We develop a N-heterocyclic carbene (NHC) and base-mediated [3+3] annulation reaction of the unsaturated carboxylic ester and sulfonium salts for the rapid and direct access to the enantioselective dihydropyrano[3,2-b]indoles. Easily...

Keywords: enantioselective construction; annulation; dihydropyranone fused; construction dihydropyranone; unsaturated carboxylic; carboxylic ester

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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