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Regio- and diastereoselective construction of conjugate oxindole derivatives enabled by delayed acyl transfer of pyridinium ylides

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Herein, we design and develop a one-pot cascade strategy for the assembly of multi-substituted conjugate oxindole derivatives. This approach represents a new reaction mode for carbene gem-difunctionalization by delayed acyl… Click to show full abstract

Herein, we design and develop a one-pot cascade strategy for the assembly of multi-substituted conjugate oxindole derivatives. This approach represents a new reaction mode for carbene gem-difunctionalization by delayed acyl transfer instead of delayed proton transfer.

Keywords: transfer; oxindole derivatives; conjugate oxindole; acyl transfer; delayed acyl

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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