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One-step Synthesis of Cyanated Pyrazolo[1, 5-a]pyridines Utilizing N-Aminopyridines as 1,3-Dipole and Nitrogen Source

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By utilizing the dual reactivity function of N-aminopyridinium ylides, we develop direct [3 + 2]-cycloadditions of N-aminopyridinium ylides and ynals to build pyrazolo[1, 5-a]pyridines core while introducing a cyano group.... Click to show full abstract

By utilizing the dual reactivity function of N-aminopyridinium ylides, we develop direct [3 + 2]-cycloadditions of N-aminopyridinium ylides and ynals to build pyrazolo[1, 5-a]pyridines core while introducing a cyano group....

Keywords: pyridines utilizing; one step; synthesis cyanated; pyrazolo pyridines; step synthesis; cyanated pyrazolo

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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