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Chemo- and Regioselective Cyclization of Diene-tethered Enynes via Palladium-Catalyzed Aminomethylamination

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A novel palladium-catalyzed cascade annulative aminomethylamination of diene-tethered enynes with aminals is described. This method provides rapid access to functionalized benzofulvenes with excellent chemo- and regioselectivities and 100% atom economy.... Click to show full abstract

A novel palladium-catalyzed cascade annulative aminomethylamination of diene-tethered enynes with aminals is described. This method provides rapid access to functionalized benzofulvenes with excellent chemo- and regioselectivities and 100% atom economy....

Keywords: aminomethylamination; tethered enynes; palladium catalyzed; diene tethered

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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