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The base-catalyzed addition of alkynylsilanes to ketone derivatives enables the formation of various silyl-protected propargylic alcohols. Commercially available and inexpensive potassium bis(trimethylsilyl)amide (KHMDS) serves as an efficient transition metal-free catalyst... Click to show full abstract
The base-catalyzed addition of alkynylsilanes to ketone derivatives enables the formation of various silyl-protected propargylic alcohols. Commercially available and inexpensive potassium bis(trimethylsilyl)amide (KHMDS) serves as an efficient transition metal-free catalyst...
Keywords:
silylacetylenes ketones;
base catalyzed;
catalyzed addition;
ketones route;
addition silylacetylenes
Journal Title: Organic Chemistry Frontiers
Year Published: 2023
Link to full text (if available)
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Journal Title: Organic Chemistry Frontiers
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!