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Pd-catalyzed imine-directed one-pot access to polysubstituted pyrroles via tandem triple isocyanide insertion/aza-Nazarov cyclization reactions

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Herein, we report a novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides. The conversion process is catalyzed by a Pd catalyst... Click to show full abstract

Herein, we report a novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides. The conversion process is catalyzed by a Pd catalyst...

Keywords: catalyzed imine; imine directed; one pot; directed one; pot access; pot

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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