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Direct Benzylic Polychlorination of (Poly)Azines with N-Chlorosuccinimide

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Herein, we describe a site-selective benzylic C–H bond chlorination of nitrogen-containing heteroarenes by low-cost N-chlorosuccinimide in acetonitrile under a catalyst- or initiator-free condition. This protocol is applicable to a wide... Click to show full abstract

Herein, we describe a site-selective benzylic C–H bond chlorination of nitrogen-containing heteroarenes by low-cost N-chlorosuccinimide in acetonitrile under a catalyst- or initiator-free condition. This protocol is applicable to a wide...

Keywords: direct benzylic; polychlorination poly; benzylic polychlorination; chemistry; poly azines; azines chlorosuccinimide

Journal Title: Organic Chemistry Frontiers
Year Published: 2023

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