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B(C6F5)3-Catalyzed Stepwise 1,5-Hydride Migration/Cyclization: Diastereoselective Construction of Carbocyclic β-Amino Acid Derivatives

Concerted 1,5-hydride migration/cyclization reactions represent an efficient approach for the construction of six-membered cyclic scaffolds. However, their applications are severely restricted by the requirement of strong electron-withdrawing functional groups, expanding... Click to show full abstract

Concerted 1,5-hydride migration/cyclization reactions represent an efficient approach for the construction of six-membered cyclic scaffolds. However, their applications are severely restricted by the requirement of strong electron-withdrawing functional groups, expanding...

Keywords: hydride migration; c6f5 catalyzed; construction; migration cyclization

Journal Title: Organic Chemistry Frontiers
Year Published: 2024

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