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Palladium-catalyzed radical arylation of N-hydroxyphthalimides with triphenyl phosphites as an unusual arylating agent via C(sp2)–O bond cleavage

An approach has been developed for producing aryl radical intermediates by utilizing readily accessible triphenyl phosphite as the radical precursor in a Pd-catalyst system under air conditions. Moreover, the possible… Click to show full abstract

An approach has been developed for producing aryl radical intermediates by utilizing readily accessible triphenyl phosphite as the radical precursor in a Pd-catalyst system under air conditions. Moreover, the possible mechanism was proposed.

Keywords: catalyzed radical; palladium catalyzed; arylation hydroxyphthalimides; radical arylation; triphenyl phosphites; hydroxyphthalimides triphenyl

Journal Title: Organic Chemistry Frontiers
Year Published: 2024

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