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Synthesis of functionalized quinolines from the cascade reactions of N-aryl amidines with two CF3-ynones via C−H/N−H/C−N/C−C bond cleavage

Presented herein is a novel synthesis of CF3- and alkynyl-substituted quinoline derivatives based on Rh(III)-catalyzed cascade reactions of N-aryl amidines with two CF3-ynones. The formation of products involves a cascade... Click to show full abstract

Presented herein is a novel synthesis of CF3- and alkynyl-substituted quinoline derivatives based on Rh(III)-catalyzed cascade reactions of N-aryl amidines with two CF3-ynones. The formation of products involves a cascade...

Keywords: aryl amidines; reactions aryl; two cf3; cascade reactions; cf3 ynones; amidines two

Journal Title: Organic Chemistry Frontiers
Year Published: 2024

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