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We compared the passive permeability of cyclosporin A (CsA) derivatives with side chain deletions across lipid bilayers. CsA maintained passive permeability after losing any one of the side chains, which… Click to show full abstract
We compared the passive permeability of cyclosporin A (CsA) derivatives with side chain deletions across lipid bilayers. CsA maintained passive permeability after losing any one of the side chains, which suggests that the propensity of the backbone of CsA is an important component for high passive permeability.
Keywords:
side chain;
passive permeability;
across lipid;
high passive;
permeability;
lipid bilayers
Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!