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We have developed broadly reactive aptamers against multiple variants by alternating the target between spike proteins from different SARS-CoV-2 variants during the selection process. In this process we have developed… Click to show full abstract
We have developed broadly reactive aptamers against multiple variants by alternating the target between spike proteins from different SARS-CoV-2 variants during the selection process. In this process we have developed aptamers which can recognise all variants, from the original wild-type ‘Wuhan’ strain to Omicron, with high affinity (Kd values in the pM range).
Keywords:
cov variants;
broadly reactive;
reactive aptamers;
high affinity;
sars cov
Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!