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Here we present an iridium catalysed C2-selective methylation of indoles using methyltrifluoroborate as a source of methyl group. The iridium catalyst selectively discriminates the indole C2 and C4 C–H bonds… Click to show full abstract
Here we present an iridium catalysed C2-selective methylation of indoles using methyltrifluoroborate as a source of methyl group. The iridium catalyst selectively discriminates the indole C2 and C4 C–H bonds by coordination with a pivaloyl directing group.
Keywords:
selective methylation;
indoles using;
iridium;
group;
methylation indoles;
iridium catalysed
Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!