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Nickel-free Cross-electrophile Coupling of Unactivated Alkyl Bromides with Thiosulfonates and Sulfinyl Sulfones

An unusual zinc-promoted reductive coupling between alkyl bromides and thiosulfonates under nickel-free conditions is described. This pracitical strategy provides an attractive approach to access a series of structure-varied sulfides which... Click to show full abstract

An unusual zinc-promoted reductive coupling between alkyl bromides and thiosulfonates under nickel-free conditions is described. This pracitical strategy provides an attractive approach to access a series of structure-varied sulfides which...

Keywords: alkyl bromides; cross electrophile; free cross; nickel free; bromides thiosulfonates

Journal Title: Organic Chemistry Frontiers
Year Published: 2024

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