Indole-based atropisomers have emerged as an important backbone in drug discovery and novel catalyst/ligand design. However, the development of asymmetric synthesis of axially chiral 2-arylindoles is sluggish due to the... Click to show full abstract
Indole-based atropisomers have emerged as an important backbone in drug discovery and novel catalyst/ligand design. However, the development of asymmetric synthesis of axially chiral 2-arylindoles is sluggish due to the...
Keywords:
friedel crafts;
axially chiral;
atroposelective friedel;
crafts alkylation;
catalytic atroposelective;
chiral arylindoles
Journal Title: Organic Chemistry Frontiers
Year Published: 2025
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Journal Title: Organic Chemistry Frontiers
Year Published: 2025
Link to full text (if available)
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recommendations!