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Cycloisomerization of 7-En-2-yn-1-ones to Bicyclo[3.1.0]hexanes Using Electrophilic Fluorination or Chlorination Agents

In contrast to the π-electrophilic transition metal-catalyzed cycloisomerization of enynes, systematic studies on the reaction of enynes by activation of carbonyl groups conjugated to alkynes are lacking. Herein, we report... Click to show full abstract

In contrast to the π-electrophilic transition metal-catalyzed cycloisomerization of enynes, systematic studies on the reaction of enynes by activation of carbonyl groups conjugated to alkynes are lacking. Herein, we report...

Keywords: ones bicyclo; cycloisomerization ones; electrophilic fluorination; using electrophilic; hexanes using; bicyclo hexanes

Journal Title: Organic Chemistry Frontiers
Year Published: 2025

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