Five new indole diterpenoids, shearinines U–Y (2–6), and the known compound 22,23-dehydro-shearinine A (1) were isolated from cultures of the entomogenous fungus Penicillium sp. Their structures were elucidated primarily by… Click to show full abstract
Five new indole diterpenoids, shearinines U–Y (2–6), and the known compound 22,23-dehydro-shearinine A (1) were isolated from cultures of the entomogenous fungus Penicillium sp. Their structures were elucidated primarily by NMR experiments. The absolute configurations of 2–6 were assigned by electronic circular dichroism calculations, respectively. Compounds 1–3 showed moderate cytotoxicity, with IC50 values of 11.7–26.2 μM.
Keywords:
indole diterpenoids;
shearinines indole;
entomogenous fungus;
fungus penicillium;
diterpenoids entomogenous
Journal Title: RSC Advances
Year Published: 2025
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Journal Title: RSC Advances
Year Published: 2025
Link to full text (if available)
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recommendations!