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One-pot acid-catalysed synthesis of bis(1-imidazo[1,5-a]pyridyl)arylmethanes and evaluation of cytotoxic activities

A practical and efficient approach for the acid-catalysed synthesis of bis(1-imidazo[1,5-a]pyridyl)arylmethane (BimPy) derivatives has been described. Interestingly, these BimPys showed potential cytotoxicity against various cancer cell lines (SK-LU-1, MCF-7, HepG2). Click to show full abstract

A practical and efficient approach for the acid-catalysed synthesis of bis(1-imidazo[1,5-a]pyridyl)arylmethane (BimPy) derivatives has been described. Interestingly, these BimPys showed potential cytotoxicity against various cancer cell lines (SK-LU-1, MCF-7, HepG2).

Keywords: imidazo pyridyl; catalysed synthesis; acid catalysed; bis imidazo; synthesis bis

Journal Title: RSC Advances
Year Published: 2025

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