A ruthenium(II)-catalyzed direct oxidative (4+3) C-H/C-H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol has been described. The developed method yielded the corresponding annulated products in moderate to good yields. In addition,… Click to show full abstract
A ruthenium(II)-catalyzed direct oxidative (4+3) C-H/C-H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol has been described. The developed method yielded the corresponding annulated products in moderate to good yields. In addition, based on the control experimental results, a possible reaction mechanism has been proposed for the (4+3) C-H/C-H annulation reaction.
Keywords:
annulation;
pyrido pyrimidin;
pyrimidin ones;
aryl pyrido;
annulation aryl;
oxidative annulation
Journal Title: Chemical communications
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Chemical communications
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!