By utilizing characteristic blocking signatures, the interactions between aflatoxin B1 (AFB1) and its aptamer were investigated. Furthermore, its aptamer sequence was evolved to have a higher affinity (Kd) calculated to… Click to show full abstract
By utilizing characteristic blocking signatures, the interactions between aflatoxin B1 (AFB1) and its aptamer were investigated. Furthermore, its aptamer sequence was evolved to have a higher affinity (Kd) calculated to be 18.74 nM for AFB1 than previous reports. This evolved aptamer-based nanopore strategy enabled the sensitive detection of trace AFB1 with a linear range from 0.5 to 100 nM.
Keywords:
aptamer;
investigation aflatoxin;
molecule investigation;
aflatoxin aptamer;
nanopore single;
single molecule
Journal Title: Chemical communications
Year Published: 2025
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Journal Title: Chemical communications
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!