A highly regio- and diastereoselective (3+3)-cycloannulation of in situ generated carbonyl ylides and 2-(1-alkynyl)-2-alken-1-ones enabled by silver catalysis is reported. This work is the first to describe a silver catalysed… Click to show full abstract
A highly regio- and diastereoselective (3+3)-cycloannulation of in situ generated carbonyl ylides and 2-(1-alkynyl)-2-alken-1-ones enabled by silver catalysis is reported. This work is the first to describe a silver catalysed synthesis of 3,4-fused furan with an oxa-bridged motif. The scope of the reaction is broad and the oxa-bridged furan products were obtained in good to high yields and with excellent regio- and diastereoselectivities.
Keywords:
ylides alkynyl;
diastereoselective cycloannulation;
carbonyl ylides;
regio diastereoselective;
alkynyl alken;
highly regio
Journal Title: Chemical communications
Year Published: 2025
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Journal Title: Chemical communications
Year Published: 2025
Link to full text (if available)
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recommendations!