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One-Pot Multienzyme-Catalyzed Assembly of Pentasaccharide Repeating Units from Group B Streptococcus Capsular Polysaccharides and Their Related Oligosaccharide Derivatives

The biochemical properties, functional characterization and substrate specificities of five recombinant glycosyltransferases – β-1,3-N-acetylglucosaminyltransferase (Cps1aI), β-1,4-galactosyltransferase (Cps1aJ), β-1,3-galactosyltransferase (Cps1bJ), and α-2,3-sialyltransferase (Cps1aK and Cps1bK) – involved in the biosynthesis of... Click to show full abstract

The biochemical properties, functional characterization and substrate specificities of five recombinant glycosyltransferases – β-1,3-N-acetylglucosaminyltransferase (Cps1aI), β-1,4-galactosyltransferase (Cps1aJ), β-1,3-galactosyltransferase (Cps1bJ), and α-2,3-sialyltransferase (Cps1aK and Cps1bK) – involved in the biosynthesis of...

Keywords: catalyzed assembly; pentasaccharide repeating; multienzyme catalyzed; one pot; assembly pentasaccharide; pot multienzyme

Journal Title: Green Chemistry
Year Published: 2025

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