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Modulation of α-synuclein AGE-based cytotoxic aggregation by zinc oxide nanoparticles: a potential therapeutic approach

The non-enzymatic posttranslational glycation, resulting in advanced glycation end product (AGE) formation, is involved in various central nervous system pathologies like Parkinson’s and Alzheimer’s diseases. α-Synuclein (αS) containing lysine residues... Click to show full abstract

The non-enzymatic posttranslational glycation, resulting in advanced glycation end product (AGE) formation, is involved in various central nervous system pathologies like Parkinson’s and Alzheimer’s diseases. α-Synuclein (αS) containing lysine residues...

Keywords: age; age based; based cytotoxic; cytotoxic aggregation; modulation synuclein; synuclein age

Journal Title: New Journal of Chemistry
Year Published: 2025

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