LAUSR

Abstract Hypertrophic cardiomyopathy (HCM), a leading cause of sudden death among athletes and young adults is not uniquely human. 1 The disorder has been diagnosed in a wide range of other mammalian species and is seen with some frequency in certain domestic animals (Figure 1). 2-16 The clinical characteristics, natural history and therapeutic interventions are similar across species. Comparative genomic analyses point to overlapping genetic basis for the disorder in humans and other animals, in particular certain domestic cat breeds. 2 , 3 , 4 , 5 , 6 Increased knowledge exchange between the fields of human and veterinary cardiology can expand how HCM is understood, treated, and potentially prevented across the tree of life.