LAUSR

Hereditary transthyretin amyloidosis is associated with gastrointestinal symptoms which can have a negative impact on quality of life [1], with gastroparesis being a frequent complication of familial amyloidotic polyneuropathy (FAP) [2]. Interventions that target symptoms while liver transplantation is awaited can be of the utmost importance for improvement of nutritional status and optimization of surgical outcomes. Gastric peroral endoscopic myotomy (G-POEM) has been described as safe with high technical and clinical success rates, mainly for postoperative, diabetic, and idiopathic gastroparesis [3]. A 38-year-old man with a genetic diagnosis of FAP and a 10-year history of neuropathic manifestations who was receiving treatment with tafamidis presented with nausea, vomiting, post-prandial epigastric pain, and weight loss, with severe E-Videos