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Endoscopic closure of cecal fistula using purse-string suture after plombage with polyglycolic acid sheets and fibrin glue.

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An 86-year-old man with a postappendectomy abscess and fistula was treated with antibiotics and percutaneous drainage for 5 weeks, but the fistula did not close (▶Fig. 1, ▶Fig. 2 a).… Click to show full abstract

An 86-year-old man with a postappendectomy abscess and fistula was treated with antibiotics and percutaneous drainage for 5 weeks, but the fistula did not close (▶Fig. 1, ▶Fig. 2 a). We report successful fistula closure using a modified endoscopic closure technique (▶Video 1). Polyglycolic acid (PGA) sheets (Neoveil; Gunze, Kyoto, Japan) were cut into 5× 5-mm pieces and delivered into the fistula through the working channel of an endoscope using biopsy forceps. Then, five pieces of PGA sheet were inserted into the fistula, and fibrin glue (Beriplast P Combi-Set; CSL Behring Pharma, Tokyo, Japan) was sprayed via a tube inserted into the fistula. Finally, the endoscope was changed to a two-channel endoscope. A detachable snare (Endoloop; Olympus, Tokyo, Japan) was anchored with clips to the mucosa around the fistula and tightened to prevent the PGA sheet pieces from falling into the cecal lumen. Radiography showed improvement of the abscess cavity at the beginning of oral feeding on postoperative day 5 (▶Fig. 2b). Closure using over-the-scope clips (Ovesco Endoscopy, Tübingen, Germany) has been a standard treatment option for gastrointestinal (GI) fistulas, but its success rate is not necessarily high [1, 2]. PGA sheets and fibrin glue have been reported as useful for treating GI fistulas [3, 4], but most reports describe successful closure in the upper GI tract; few have reported on lower GI fistulas. It is difficult to keep PGA sheets within lower GI fistulas because of peristalsis and stool. An endoE-Videos

Keywords: closure; polyglycolic acid; endoscopic closure; fistula; fibrin glue; sheets fibrin

Journal Title: Endoscopy
Year Published: 2022

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