LAUSR

A 21-year-old man presented to our hospital with profuse hematochezia. He reported having been admitted at another hospital 2 years earlier due to a hemoglobin (Hb)-relevant lower gastrointestinal bleed. At that time, the diagnostic workup (including a capsule endoscopy and a red blood cell scintigraphy) failed to reveal the cause of bleeding. At current admission, gastroscopy showed no pathological findings and the initial Hb level was stable at 13.2g/dL. The following night, the patient again developed hematochezia with concomitant tachycardia (130bpm) while Hb levels rapidly dropped to 7.3 g/dL. An emergency colonoscopy, computed tomography (CT) angiography, and an oral single-balloon enteroscopy (SBE) failed to detect the origin of the hemorrhage. A second SBE was performed by anal approach and showed a diverticulum adjacent to a mucosal lesion located 100cm proximal to the ileocecal valve with an eroded vessel (▶Fig. 1). The application of a metal clip prevented further bleeding (▶Video 1). Technetium-99m scintigraphy (Meckel’s scan) supported the diagnosis of a Meckel’s diverticulum (▶Fig. 2). The diagnosis was later confirmed in the surgical specimen (▶Fig. 3 a). Histopathological examination found gastric mucosa inside the diverticulum and two ulcers at the marginal region (▶Fig. 3b). Meckel’s diverticulum occurs in 0.3%– 2.9% of the population [1]. Bleeding is most often seen in children aged 2 years or younger and typically occurs because the acidic secretions produced by ectopic gastric mucosa within the diverticulum erode the adjacent intestinal mucosa [1]. Meckel’s scan has high specificity but limited sensitivity for Meckel’s diverticulum [2]. In addition, as exemplified by this case, Meckel’s diverticulum may not be identified by CT angiography owing to intermittent bleeding and can be overlooked by capsule endoscopy. In the current case, SBE not only allowed Meckel’s diverticulum to be diagnosed but was also used to prevent bleeding recurrence by the application of metal clips, which also served to guide the subsequent surgical excision of the Meckel’s diverticulum. Endoscopy_UCTN_Code_CCL_1AC_2AF