A novel nickel-catalyzed chemoselective cascade reaction strategy towards the synthesis of benzo[b]azepine was developed. The method is characterized by simple and mild conditions, low cost, and a wide range of… Click to show full abstract
A novel nickel-catalyzed chemoselective cascade reaction strategy towards the synthesis of benzo[b]azepine was developed. The method is characterized by simple and mild conditions, low cost, and a wide range of substrates. The method enables the facile and efficient synthesis of a series of 2,3,4,5-tetrahydro-1H-benzo[b]azepine analogues appended a fluorinated sidechain.
               
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